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Protein synthesis at the synapse: Developmental changes, subcellular localization and regional distribution of polypeptides synthesized in isolated dendritic fragments
(2001)
This study evaluated local protein synthesis in subcellular fractions of pinched-off dendrites (synaptodendrosomes) from different brain regions and at different developmental ages. Synaptodendrosomes were labeled with ...
Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus
(2015)
Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins expressed in the brain. One such autoantibody targets myelin basic protein (MBP). ASD patients have autoantibodies to MBP of both ...
Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus
(2015)
Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins expressed in the brain. One such autoantibody targets myelin basic protein (MBP). ASD patients have autoantibodies to MBP of both ...
Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus
(Elsevier, 2015)
Autoantibodies from autistic spectrum disorder (ASD) patients react with multiple proteins expressed in the
brain. One such autoantibody targets myelin basic protein (MBP). ASD patients have autoantibodies to MBP of
both ...
Synaptic localization of acylpeptide hydrolase in adult rat telencephalon
(ELSEVIER IRELAND LTD, 2012)
Acylpeptide hydrolase (ACPH), a serine protease present in the central nervous system (CNS), is believed to have a function in modulating synaptic plasticity, cleavage of beta amyloid peptide and degradation of aggregated ...
Synaptic Homeostasis and Restructuring across the Sleep-Wake Cycle
(Aldo A Faisal, Imperial College London, UNITED KINGDOM, 2015-05-28)
Sleep is critical for hippocampus-dependent memory consolidation. However, the underlying
mechanisms of synaptic plasticity are poorly understood. The central controversy is on
whether long-term potentiation (LTP) takes ...
Wnt - 7a Modulates the Synaptic Vesicle Cycle and Synaptic Transmission in Hippocampal Neurons
(2008)
Wnt signaling is essential for neuronal development and the maintenance of the developing nervous system. Recent studies indicated that Wnt signaling modulates long term potentiation in adult hippocampal slices. We report ...
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. is there a role in Alzheimer's disease?
(2011)
Amyloid β-peptide (Aβ) is the main component of the amyloid plaques associated with Alzheimer's disease (AD). In the early steps of the disease soluble Aβ oligomers are produced. According to the current "amyloid hypothesis" ...
Alcohol impairs hippocampal function: From NMDA receptor synaptic transmission to mitochondrial function
(Elsevier Ireland Ltd, 2019)